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San Francisco 49ers
San Francisco 49ers
4th in NFC West 6-11-0 Overall 1-5-0 NFC
2024-25 REGULAR SEASON
260.2 PYPG
127.2 RYPG
22.9 PPG
376.3 TotY/G

San Francisco 49ers Injury Report

Last Updated: Jan 21, 2025 | 01:30 AM ET
PLAYER
POSITION
INJURY
STATUS
EST. RETURN
Brandon Aiyuk
WR
Leg - Knee - ACL + MCL
IR
Feb 10
Aaron Banks
OG
Leg - Knee - MCL
IR
Feb 10
Ben Bartch
OG
Leg - Ankle
IR
Feb 10
Robert Beal
DE
Leg - Ankle
Questionable
Feb 10
Spencer Burford
OG
Leg - Calf
IR
Feb 10
De'Vondre Campbell
LB
Other - Suspension
Reserve - SUS
Feb 10
Chris Conley
WR
Arm - Elbow
Questionable
Feb 10
Jon Feliciano
OG
Leg - Knee
IR
Feb 10
Demetrius Flannigan-Fowles
LB
Leg - Calf
IR
Feb 10
Kevin Givens
DT
Torso - Pectoral
IR
Feb 10
Renardo Green
CB
Groin
Questionable
Feb 10
Dre Greenlaw
LB
Leg - Calf
IR
Feb 10
Isaac Guerendo
RB
Leg - Knee - MCL
Questionable
Feb 10
Javon Hargrave
DT
Arm - Triceps
IR
Feb 10
Talanoa Hufanga
S
Head - Concussion
Questionable
Feb 10
Drake Jackson
DE
Leg - Knee
PUP-R
Feb 10
Deommodore Lenoir
CB
Arm - Shoulder
Questionable
Feb 10
Darrell Luter
CB
Groin - Pelvis
IR
Feb 10
Jordan Mason
RB
Leg - Ankle
IR
Feb 10
Christian McCaffrey
RB
Leg - Knee - PCL
IR
Feb 10
Colton McKivitz
OT
Other - Undisclosed
Questionable
Feb 10
Elijah Mitchell
RB
Leg - Hamstring
IR
Feb 10
Jaylon Moore
OT
Leg - Quadriceps
IR
Feb 10
Malik Mustapha
S
Leg - Knee
Questionable
Feb 10
George Odum
S
Leg - Knee
IR
Feb 10
Brock Purdy
QB
Arm - Elbow
Questionable
Feb 10
Curtis Robinson
LB
Leg - Knee - ACL
IR
Feb 10
Deebo Samuel
WR
Torso - Ribs
Questionable
Feb 10
Trent Williams
OT
Leg - Ankle
IR
Feb 10
Mitch Wishnowsky
P
Torso - Back
IR
Feb 10
No players available based on the filters applied
PUP-PL
Physically Unable to Perform (Pre-season)
PUP-R
Physically Unable to Perform (Regular Season)
IR
Injured Reserve
NFI - A
Non-football Injury (Active)
NFI - R
Non-football Injury (Reserve)
RESERVE - DNR
Reserve - Did Not Report
RESERVE - RET
Reserve - Retired
RESERVE - SUS
Reserve - Suspended
FP
Full Participant
LP
Limited Participant

Unfortunately, injuries are part of the NFL season. Each week, players get hurt – with some being more serious than others. The San Francisco 49ers have dealt with quite a few injuries as of late. Let’s break down the Niners’ various injuries, including who is on injured reserve, their latest injury report, and more.

Which San Francisco 49ers Players Are Currently On the IR?

The following 49ers players are currently on injured reserve:

  • Talanoa Hufanga, S — Wrist — Week to Week (IR)
  • Mitch Wishnowski, P — Back — Week to Week
  • Darrell Luter, CB — Pelvis — Week to Week
  • Jon Feliciano, OG — Knee — Week to Week (IR)
  • Dre Greenlaw, LB — Achilles — Week to Week (PUP-R)
  • Ambry Thomas, CB — Forearm — Week to Week (IR)
  • Brandon Aiyuk, WR — ACL, MCL — Out For Season (IR)
  • Javon Hargrave, DT — Triceps — Out For Season (IR)
  • Drake Jackson, DE — Knee — Out For Season (PUP-R)
  • Elijah Mitchell, RB — Hamstring — Out For Season (IR)
  • Curtis Robinson, LB — ACL — Out For Season (IR)

Which 49ers Players Are On the Injury Report?

The following 49ers players were listed on the team’s most-recent injury report ahead of their Week 8 showdown against the Dallas Cowboys on Sunday Night Football.

  • Tatum Bethune, LB — Knee — Questionable
  • Nick Bosa, DE — Hip — Questionable
  • Jacob Cowing, WR — Concussion — Questionable
  • Kevin Givens, DT — Groin — Questionable
  • George Kittle, TE — Hamstring — Questionable
  • Brock Purdy, QB — Shoulder — Questionable
  • Trent Williams, OT — Ankle — Questionable

What Is IR and How Does It Work?

IR stands for injured reserve. A player is added to IR if they are dealing with a football-related injury and will miss a significant period of time. Players on the IR list don't count against the active roster, meaning teams can sign temporary replacements without going over the maximum 53 players.

If a player is placed on the IR list prior to the start of the season, their season is over. If they are placed on the list during the season, they must miss a minimum of four games before they can return.

Once a player is healthy enough to practice, they must be designated for a return. This designation clears the player to resume practicing and triggers a 21-day window during which the team must either activate the player onto the 53-man roster or place them on season-ending injured reserve.

Teams can designate up to eight players for return from injured reserve during the season. However, each player can be designated for return only twice.

The physically unable to perform (PUP) list and non-football injury (NFI) list have similar rules. The PUP list is a roster designation for players who were injured before training camp. The NFI list is for players who suffered an injury away from football or prior to entering the NFL (like during their collegiate career).

When Do NFL Injury Reports Come Out?

A team’s practice reports are different from the weekly injury report. The practice report details whether injured players were able to participate in practice. There are three levels of player participation in the practice report: Did Not Participate, Limited Participation, and Full Participation. The league defines limited participation as anything less than 100% of a player’s normal repetitions.

Teams are required to put out a practice report three times during the week leading up to the game. For Sunday games, teams must release their practice reports on Wednesday, Thursday, and Friday. For a Monday Night Football game, practice reports must be released on Thursday, Friday, and Saturday. For a Thursday Night Football game, they are released on Monday, Tuesday, and Wednesday.

Finally, the injury report (or game-status report) is where players are designated as questionable, doubtful, or out. For Sunday games, the injury report must be released by 4 p.m. ET on Friday. For Monday Night Football games, it must be released by 4 p.m. ET on Saturday. For Thursday Night Football games, it must be released by 4 p.m. ET on Wednesday. The team must report if a player's condition changes after the initial injury report is released.