We have a four-game slate in the late afternoon window, including an exciting matchup between the Buffalo Bills and Philadelphia Eagles. We break each of these four games down with the odds and our NFL Week 12 predictions, picks against the spread, and more.
NFL Week 12 Predictions and Picks for the Late Afternoon
Los Angeles Rams vs. Arizona Cardinals Odds
- Spread
Rams -2.5 - Moneyline
Rams -142, Cardinals +120 - Total
45.5
Blewis: The last time this Rams offense was at full strength, they put up 26 points against this Cardinals defense that was healthier than they are now. In that game, Matthew Stafford averaged 9.4 YPA, and Williams ran for 158 yards on 7.9 YPC.
MORE: NFL Against the Spread Standings
With a fully healthy offense, I’m expecting the Rams to put up a lot of points against an atrocious Cardinals defense.
Pick: Rams over 23.5 (-110 at DraftKings)
Cleveland Browns vs. Denver Broncos Odds
- Spread
Broncos -1.5 - Moneyline
Browns +100, Broncos -118 - Total
37
Bearman: Combined, these two teams are 8-2 over the last five weeks. And both are winning with defense, with the Browns bringing in the top defense in terms of yards allowed and the Broncos looking nothing like the team that gave up 70 to Miami earlier this season.
You know what I love to do with a defensive battle — DTR at QB for the Browns, and Russ still not cooking in Denver? The under.
Pick: Under 36.5 (-118 at FanDuel)
Katz: My jaw almost dropped when I saw this line. Last week, we just barely cashed on Dorian Thompson-Robinson’s passing yards under by 2.5 yards. That was against a weaker Steelers pass defense than the Broncos have and in a game where he attempted 43 passes.
This week, DTR gets a much tougher opponent, and he is not going to throw more than 40 passes. The Broncos have been much-improved against the pass over the past month. Meanwhile, they still struggle against the run. We should see a lot of Jerome Ford and not a lot of Thompson-Robinson throwing the ball. With nine more yards to play with than last week, I love this under.
Pick: Dorian Thompson-Robinson under 176.5 passing yards (-114 at FanDuel)
Kansas City Chiefs vs. Las Vegas Raiders Odds
- Spread
Chiefs -9.5 - Moneyline
Chiefs -500, Raiders +385 - Total
43.5
Blewis: Before they blew a 10-point lead, the Chiefs defense did an incredible job of shutting down Jalen Hurts and the Eagles offense last week. Now, they’ll be facing Aidan O’Connell, who, for the most part, has looked like a rookie quarterback drafted in the fourth round.
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I don’t have much confidence in the Raiders offense here, but I do think their defense can prevent the Chiefs from putting up a ton of points. For the season, they’re now 14th in EPA/play and 16th in DVOA.
Even if I have little faith in their offense, I do think their running game can slow this game down a bit and keep the Chiefs offense off the field. For the season, the Chiefs are allowing the 28th-most rushing yards per attempt. This was on full display last week when D’Andre Swift averaged 6.3 yards per carry.
Pick: Under 43.5 (-112 at DraftKings)
Buffalo Bills vs. Philadelphia Eagles Odds
- Spread
Eagles -3 - Moneyline
Bills +136, Eagles -162 - Total
48.5
Blewis: I’m going to need to see two good performances in a row by this Eagles defense, most notably against the pass, to fully buy in. While limiting Patrick Mahomes to 177 passing yards on just 4.1 yards per attempt is impressive no matter how you slice it, they got bailed out by a number of drops from the Chiefs wide receivers.
Last week, the Eagles weren’t afraid of any Chiefs pass catcher outside of Travis Kelce — that game plan won’t work against the Bills, who have more depth around Stefon Diggs.
Pick: Bills over 23.5 (+100 at DraftKings)
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