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    Patriots vs. 49ers Inactives and Takeaways: Week 4 Injury Reports and Starting Lineups

    Here's everything you need to know about the injuries and inactives lists for Sunday's game between the New England Patriots and San Francisco 49ers.

    Are the New England Patriots the team we saw exceeding expectations the first two weeks, or the one that was blown out by the New York Jets in Week 3?

    We’ll get an answer Sunday afternoon when Jerod Mayo and company visit Kyle Shanahan and the San Francisco 49ers. Both teams are 1-2 and dealing with key injuries, though the Patriots enter the matchup as 10.5-point underdogs.

    But which players will be on the field for each team? Let’s go over inactives, injury designations, and projected lineups.

    Who Are the Inactives for New England Patriots vs. San Francisco 49ers?

    Patriots Inactives vs. 49ers

    Here’s the full inactives list for the Patriots:

    • QB Joe Milton III (emergency third QB)
    • LB Anfernee Jennings
    • DE Jamree Kromah
    • OT Vederian Lowe
    • G Mike Jordan
    • TE Jaheim Bell

    49ers Inactives vs. Patriots

    Here’s the 49ers’ full inactives list:

    • QB Joshua Dobbs (emergency third QB)
    • WR Ronnie Bell
    • CB Darrell Luter
    • S Talanoa Hufanga
    • G Ben Bartch

    Patriots-49ers Inactives Takeaways

    • Anfernee Jennings, who is dealing with a shoulder injury, is a tough loss for the Patriots. Here’s their best run-stuffing outside linebacker and one of their most consistent defenders.
    • Jamree Kromah is a healthy scratch for the second consecutive game after being signed off the Chicago Bears’ practice squad.
    • Jaheim Bell is a healthy scratch and will be replaced on the tight end depth chart by Mitchell Wilcox, who was elevated from the practice squad.
    • The biggest news for the 49ers is that receiver Deebo Samuel Sr. will play after missing last week due to a calf injury.
    • Tight end George Kittle already will play, which we knew after San Francisco released its final Week 4 injury report.

    Latest Injury Report News and Updates

    Here are the final Week 4 injury reports for both teams:

    Patriots

    OUT

    • CB Alex Austin, Ankle
    • OT Vederian Lowe, Knee
    • G Mike Jordan, Ankle

    DOUBTFUL

    • No players listed

    QUESTIONABLE

    • EDGE Anfernee Jennings, Shoulder
    • CB Jonathan Jones, Shoulder
    • G Sidy Sow, Ankle
    • OT Caedan Wallace, Knee

    49ers

    OUT

    DOUBTFUL

    • No players listed

    QUESTIONABLE

    • WR Deebo Samuel Sr., Calf
    • OT Trent Williams, Illness, Toe
    • LB Dee Winters, Ankle
    • DT Jordan Elliott, Foot
    • S Talanoa Hufanga, Ankle

    Samuel reportedly plans to play Sunday after sitting out last week, according to NFL insider Jordan Schultz. Williams also is expected to suit up.

    Projected Patriots Week 4 Starting Lineups

    Lineups won’t be confirmed until after Sunday’s 4:05 p.m. kickoff, but here’s an educated guess at New England’s positional groupings:

    Quarterback

    Starter: Jacoby Brissett

    Backups: Drake Maye, Joe Milton III (emergency third QB)

    Running Back

    Starter: Rhamondre Stevenson

    Backups: Antonio Gibson, JaMycal Hasty

    Wide Receiver

    Starters: DeMario Douglas, K.J. Osborn, Tyquan Thornton

    Backups: Ja’Lynn Polk, Javon Baker, Kayshon Boutte

    Tight End

    Starter: Hunter Henry

    Backups: Austin Hooper, Mitchell Wilcox

    Offensive Line

    Starters: Demontre Jacobs, Sidy Sow, David Andrews, Layden Robinson, Mike Onwenu

    Backups: Nick Leverett, Zach Thomas, Caedan Wallace

    Defensive Tackle

    Starters: Deatrich Wise Jr., Davon Godchaux, Daniel Ekuale

    Backups: Jeremiah Pharms Jr., Eric Johnson II, Trysten Hill

    EDGE

    Starters: Keion White, Joshua Uche

    Backups: Curtis Jacobs

    Linebacker

    Starters: Raekwon McMillan, Jahlani Tavai

    Backups: Christian Elliss

    Cornerback

    Starters: Christian Gonzalez, Jonathan Jones, Marcus Jones

    Backups: Marco Wilson, Marcellas Dial Jr., Isaiah Bolden

    Safety

    Starters: Jabrill Peppers, Kyle Dugger

    Backups: Jaylinn Hawkins, Dell Pettus, Brenden Schooler

    Special Teams

    Kicker: Joey Slye

    Punter: Bryce Baringer

    Long Snapper: Joe Cardona

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