The NFL Week 8 betting odds are centered around some key divisional matchups concluding with the Detroit Lions trying to keep their hot start going on Monday night.
How are we using these trends? The PFN Betting Podcast runs through every single game as we head into the weekend!
Our Betting Lines page has the freshest lines and promos to get BANG for your buck. PFN’s FREE Parlay Calculator and Betting Odds Calculator are also available for your betting process! New to sports betting? Check out our guide on How to Bet on the NFL. Visit our Sports Betting Legal Tracker on how to bet legally in the U.S.
NFL Week 8 Odds and Betting Trends
All odds are from DraftKings Sportsbook and trends from Inside Edge.
Tampa Bay Buccaneers vs. Buffalo Bills Odds
-
- Spread
Bills -8.5 - Moneyline
Buccaneers +320, Bills -410 - Total
42
- Spread
No team is worse against the spread (ATS) since the beginning of 2021 when coming off a loss than the Tampa Bay Buccaneers (3-9, they lost to Atlanta last weekend).
Unders are 13-4 in Buffalo’s past 17 games against bottom-10 offenses.
Philadelphia Eagles vs. Washington Commanders Odds
-
- Spread
Eagles -7 - Moneyline
Eagles -298, Commanders +240 - Total
43.5
- Spread
The Philadelphia Eagles are just 10-11 ATS on the road since the beginning of 2021.
After reaching 30 points once in 16 meetings with the Eagles, the Washington Commanders have hit that threshold in each of their past two showdowns.
New England Patriots vs. Miami Dolphins Odds
-
- Spread
Dolphins -9.5 - Moneyline
Patriots +360, Dolphins -470 - Total
47
- Spread
The New England Patriots are just 3-6 ATS in their past nine warm-weather games (early projections for Sunday: 80+ degrees).
MORE: NFL MVP Odds — Can Tua Tagovailoa, Jalen Hurts, or Lamar Jackson Challenge Patrick Mahomes?
The Miami Dolphins have won all three home games against New England in the post-Tom Brady era (in those games, the Pats have managed just 14.3 points per game).
New York Jets vs. New York Giants Odds
-
- Spread
Jets -2.5 - Moneyline
Jets -142, Giants +120 - Total
36.5
- Spread
This is technically a road game for Gang Green, and they’ve covered seven of 11 road games since the beginning of last season.
Unders are 14-4-2 when the New York Giants play at home since 2021 (77.8% cash rate, the highest in the league).
Los Angeles Rams vs. Dallas Cowboys Odds
-
- Spread
Cowboys -6 - Moneyline
Rams +210, Cowboys -258 - Total
45
- Spread
The Los Angeles Rams are 2-9 ATS against top-10 defenses since the beginning of 2021, the worst cover rate in such spots in the NFL.
Since 2021, no team has been better ATS when favored than the Dallas Cowboys (21-9).
Houston Texans vs. Carolina Panthers Odds
-
- Spread
Texans -3 - Moneyline
Texans -155, Panthers +130 - Total
43.5
- Spread
Under tickets have come through in 13 of the Houston Texans’ past 20 road games.
The Carolina Panthers have covered four of their past five games when getting three or fewer points (opened as three-point ‘dogs).
Jacksonville Jaguars vs. Pittsburgh Steelers Odds
-
- Spread
Jaguars -2.5 - Moneyline
Jaguars -142, Steelers +120 - Total
42
- Spread
Overs are 8-3 in the Jacksonville Jaguars past 11 road games.
The Pittsburgh Steelers are 5-2 ATS since the beginning of last season when getting three or fewer points (opened as a 2.5-point home favorite).
Atlanta Falcons vs. Tennessee Titans Odds
-
- Spread
Falcons -2.5 - Moneyline
Falcons -135, Titans +114 - Total
36.5
- Spread
The Atlanta Falcons are just 3-12 ATS in their past 15 games following an outright win.
Unders are 14-5 in Tennessee Titans’ home games since the beginning of 2021.
New Orleans Saints vs. Indianapolis Colts Odds
-
- Spread
Colts -1.5 - Moneyline
Saints +100, Colts -120 - Total
43.5
- Spread
Only the Giants (70%) have cashed unders at a higher rate than the New Orleans Saints (68.3%) since the beginning of 2021.
Under tickets have cashed in 10 of the Indianapolis Colts’ past 15 games when favored.
Minnesota Vikings vs. Green Bay Packers Odds
-
- Spread
Packers -1 - Moneyline
Vikings -112, Packers -108 - Total
43.5
- Spread
The Minnesota Vikings fail to cover 60% of the time during the Kirk Cousins era when at a rest disadvantage (overs have also hit at a 60% clip in those spots).
The home team has swept this series in each of the past two seasons, out-scoring the road team 135-65 in the process.
Cleveland Browns vs. Seattle Seahawks Odds
-
- Spread
Seahawks -3 - Moneyline
Browns +136, Seahawks -162 - Total
40
- Spread
The Cleveland Browns are 0-5 ATS following a road win since 2021.
The Seattle Seahawks are just 4-9 ATS vs. top-10 rush defenses since 2021.
Kansas City Chiefs vs. Denver Broncos Odds
-
- Spread
Chiefs -8 - Moneyline
Chiefs -360, Broncos +285 - Total
46
- Spread
The Kansas City Chiefs have won 16 straight over the Denver Broncos. They’ve won eight straight in Denver, scoring at least 27 points in every one of those games.
The Broncos have covered just four of their past 11 games following an outright win.
Baltimore Ravens vs. Arizona Cardinals Odds
-
- Spread
Ravens -8.5 - Moneyline
Ravens -410, Cardinals +320 - Total
43.5
- Spread
Unders are 12-1 since the beginning of 2021 when the Baltimore Ravens play a bottom-10 offense.
MORE: NFL Survivor Picks Week 8 — Are the Ravens, Lions, and Texans Good Options This Week?
The Arizona Cardinals have covered 10 of their past 14 games against top-10 pass defenses (Baltimore allows 4.5 yards per pass, more than a yard better than any other defense through seven weeks).
Cincinnati Bengals vs. San Francisco 49ers Odds
-
- Spread
49ers -5.5 - Moneyline
Bengals +195, 49ers -238 - Total
45
- Spread
Under tickets have cashed in each of the Cincinnati Bengals’ past five games against top-10 offenses.
The San Francisco 49ers are 7-4 ATS following a loss since 2021 (fourth-best rate in the league).
Chicago Bears vs. Los Angeles Chargers Odds
-
- Spread
Chargers -8.5 - Moneyline
Bears +320, Chargers -395 - Total
46.5
- Spread
At 17-10, the Chicago Bears own the highest over hit rate in non-divisional games since the beginning of 2021 (overs are 6-8 when they stay within the NFC North over that stretch).
Overs are 10-2-2 following the Los Angeles Chargers’ past 14 losses, the highest rate in the league over that period.
Las Vegas Raiders vs. Detroit Lions Odds
-
- Spread
Lions -8 - Moneyline
Raiders +300, Lions -380 - Total
45.5
- Spread
The Las Vegas Raiders are the third-worst road ATS team since the beginning of last season at 4-9.
The Lions are a league-best 15-5 ATS at home during the Jared Goff era.