We are now one-third of the way through the NFL season, and Week 7 is bringing us a league-low 13 games and no international matchups. We also have no undefeated teams left after upsets to the Philadelphia Eagles and San Francisco 49ers last week. What does this week have in store? Here are some NFL Week 7 predictions, picks against the spread, and more for the upcoming slate.
Our Betting Lines page has the freshest lines and promos to get BANG for your buck. PFN’s FREE Parlay Calculator and Betting Odds Calculator are also available for your betting process! New to sports betting? Check out our guide on How to Bet on the NFL. Visit our Sports Betting Legal Tracker on how to bet legally in the U.S.
What Are the Week 7 Odds and Betting Lines?
All odds are from FanDuel Sportsbook.
Jacksonville Jaguars vs. New Orleans Saints Odds
- Spread
Saints -1.5 - Moneyline
Jaguars +100, Saints -118 - Total
39.5
Two weeks ago, I would’ve hopped all over the New Orleans Saints in this matchup — the Jacksonville Jaguars‘ offense was terrible. A trip to London seems to have revived the offense, but now, they face the unknown with QB Trevor Lawrence’s knee injury.
Meanwhile, New Orleans enters with a top-five defense and an underperforming offense. All six Saints games have gone under the total this season, so that’s where I am headed here.
NFL Pick and Prediction: Under 39.5
Cleveland Browns vs. Indianapolis Colts Odds
- Spread
Browns -2.5 - Moneyline
Browns -124, Colts +106 - Total
39.5
What to make of the Cleveland Browns? QB Deshaun Watson, his backups, and the offense have continued to struggle, but their defense tops the league. You are likely looking at a matchup of backup QBs here — especially the Indianapolis Colts — so I want no part of a side. Yes, another under, please.
NFL Pick and Prediction: Under 39.5
Washington Commanders vs. New York Giants Odds
- Spread
Commanders -2 - Moneyline
Commanders -134, Giants +114 - Total
39.5
The New York Giants have not scored an offensive TD since this country had 48 states. Seriously though, it’s been since Week 3 — 13 quarters ago. I know, you are thinking, “Another under?” However, the Washington Commanders‘ defense is not good.
MORE: Prisoner Who Won a Massive NFL Parlay To Pay His Bond Goes Viral
The Commanders had a nice road win in Atlanta last week to end a three-game slide, but I don’t trust their defense. One thing I do know is that opposing WR1s have topped 100 yards in each of the last five games against Washington. It’s WR Jalin Hyatt’s breakout game.
NFL Pick and Prediction: Hyatt over receiving total (not posted yet)
Atlanta Falcons vs. Tampa Bay Buccaneers Odds
- Spread
Buccaneers -2.5 - Moneyline
Falcons +124, Buccaneers -146 - Total
38.5
This line confuses me. The Atlanta Falcons have shown us absolutely nothing since their 2-0 start, only winning in the final seconds vs. the Houston Texans in QB Desmond Ridder’s one shining moment.
I’m not saying the Tampa Bay Buccaneers are all-world, but this line implies they are even, as the 2.5 points given are mostly for home-field advantage. They are not even.
NFL Pick and Prediction: Buccaneers -2.5
Buffalo Bills vs. New England Patriots Odds
- Spread
Bills -8.5 - Moneyline
Bills -390, Patriots +310 - Total
41.5
These aren’t your dad’s New England Patriots. Bill Belichick’s Brady-less team has not topped 20 points this season. They are averaging 12 points per game, which we’d all be talking about if it wasn’t for the Giants being even worse.
MORE: Is Bill Belichick on the Hot Seat?
The Buffalo Bills got their scare on Sunday night, and I don’t trust them, but I would avoid taking the points. Instead, I am going to play the Patriots’ team total under, as they have 20 total points in the last three weeks.
NFL Pick and Prediction: Patriots team total under 15.5
Las Vegas Raiders vs. Chicago Bears Odds
- Spread
Raiders -3 - Moneyline
Raiders -164, Bears +138 - Total
37.5
This is another game that will likely feature backup QBs. Las Vegas Raiders signal-caller Jimmy Garropolo and Chicago Bears sensation Justin Fields are both likely out for this one. I can’t advise anyone to lay two on the road with a Raiders team that has broken 20 one time this year, nor would I advise taking the Bears at any point.
I lean under, but I also don’t trust the Bears’ putrid defense, so proceed at your own risk here.
NFL Pick and Prediction: Lean under 37.5
Detroit Lions vs. Baltimore Ravens Odds
- Spread
Ravens -3 - Moneyline
Lions +130, Ravens -154 - Total
41.5
If you haven’t bought a ticket on the “Detroit Lions Express,” you can still jump on — they are still getting points here. The Lions are an OT loss away from being the lone unbeaten team in the NFL, and that includes four straight wins by two TDs or more. They are playing like the best team in football and not getting the attention the other 5-1 teams are getting, which is fine because we like points.
The Baltimore Ravens just played in London and did not have their bye after the win over Tennessee. Every time you believe in the Ravens, they give one back, and that was against the Pittsburgh Steelers and Indianapolis — not a good Lions team.
NFL Pick and Prediction: Lions +3
Pittsburgh Steelers vs. Los Angeles Rams Odds
- Spread
Rams -3 - Moneyline
Steelers +136, Rams -162 - Total
42.5
To be honest, nothing would surprise me in this matchup. Both teams have shown playoff tendencies and have also been complete no-shows in games this season.
The Los Angeles Rams showed both last week against the Arizona Cardinals, deciding not to start playing until the second half. The Pittsburgh Steelers have been a coin flip all season. With L.A. down to a rookie, third-string RB, I lean toward Pittsburgh, but I don’t trust them.
NFL Pick and Prediction: Pass, but lean Steelers +3
Arizona Cardinals vs. Seattle Seahawks Odds
- Spread
Seahawks -7.5 - Moneyline
Cardinals +315, Seahawks -400 - Total
44.5
To borrow a line from former ESPN host Doug Kezirian: “Betting is about isolating certain aspects of the game.” The Arizona Cardinals likely won’t win this one and might not even cover, but where they have shined this season is in the first half. They are 5-1 ATS in the first two quarters and have led outright in four of them.
I lean towards the Seattle Seahawks for the game, but the hook scares me away, so I will isolate the first half. I would consider using Seattle in teaser legs at -1.5 with the Miami Dolphins at +8 or San Francisco at -0.5.
NFL Pick and Prediction: Arizona 1H +4.5
Los Angeles Chargers vs. Kansas City Chiefs Odds
- Spread
Chiefs -5.5 - Moneyline
Chargers +194, Chiefs -230 - Total
49.5
Every part of me wants to lay the points against a Los Angeles Chargers team on short rest. But when looking at the numbers, not only do the Kansas City Chiefs struggle to cover bigger numbers, they also rarely blow out the Chargers.
MORE: Week 7 NFL Power Rankings
The last time Kansas City beat them by more than six points was in 2019. Additionally, the Chargers have lost by six or more just once in the last 13 games. They seem to be playing close games every week.
NFL Pick and Prediction: Pass, but lean Chiefs -5.5
Green Bay Packers vs. Denver Broncos Odds
- Spread
Packers -1.5 - Moneyline
Packers -118, Broncos +100 - Total
45
This is not a game I will have any money on. Both teams are coming off much-needed byes. The Green Bay Packers have lost back-to-back games to the Lions and Raiders and looked terrible in both. The Denver Broncos‘ only claim to fame is a come-from-behind win against the lowly Bears.
NFL Pick and Prediction: Pass
Miami Dolphins vs. Philadelphia Eagles Odds
- Spread
Eagles -2 - Moneyline
Dolphins +112, Eagles -132 - Total
51.5
Only two of the Miami Dolphins‘ six games this season have stayed under 60 total points. One was against Belichick and the Patriots, while the other was against a Giants team when the Dolphins played backups in the second half.
The Philadelphia Eagles are banged up, and if OL Lane Johnson is out, I can see Miami winning this one as an underdog. Still, Miami also lost to the only good team they played this season — the Buffalo Bills. Either way, I expect a lot of points from both of these teams.
NFL Pick and Prediction: Over 51.5
San Francisco 49ers vs. Minnesota Vikings Odds
- Spread
49ers -6.5 - Moneyline
49ers -300, Vikings +245 - Total
44
The look-ahead line on this one closed at -7.5. The Minnesota Vikings‘ win and the San Francisco 49ers‘ first loss of the season caused the line to drop to 6.5.
Yes, the ‘Niners are banged up, but they’re also the much better team here. Without star Minnesota WR Justin Jefferson, the Vikings are going to have a lot of trouble moving the ball. As long as it stays under seven, I’m in.
NFL Pick and Prediction: Niners -6.5