There are four weeks left in the regular season, but not much has been decided in terms of the postseason. 30 of the 32 teams are still alive, making almost every game matter for our NFL picks. So, after a review of the NFL betting lines, it’s time to make my picks. Here are my NFL Week 15 predictions and picks against the spread.
NFL Week 15 Predictions and Picks Against the Spread
All odds are from ESPN BET — sign up today and use promo code PFN when registering to secure $250 in bonus bets!
Los Angeles Chargers vs. Las Vegas Raiders Prediction
- Spread
Raiders -3 - Moneyline
Chargers +125, Raiders -145 - Total
34.5
Easton Stick will be starting at QB for the Chargers and is facing a team that scored zero points last week and has topped 21 just once all season. Oh yeah, and the Chargers themselves only scored seven last week and have 23 total points in the last three games with Justin Herbert. Not sure I even need to say more.
For those that have gotten used to some scoring on TNF the last few weeks, as Eminem would say, “Back to Reality.”
Picks: Under 34.5 (best bet), Raiders team total under 19.5
Minnesota Vikings vs. Cincinnati Bengals Prediction
- Spread
Bengals -3 - Moneyline
Vikings +145, Bengals -170 - Total
40.5
I like what I have seen so far from Jake Browning since he has taken over in Joe Burrow’s absence. He has completed over 75% of his passes and has thrown for over 900 yards in 3+ games. Just when you thought the Bengals’ season was over, Browning has led them to two consecutive wins, keeping them right in the playoff race.
MORE: NFL Week 15 Odds and Betting Trends Against the Spread
While the Vikings are alive and fighting for a playoff spot as well, I’ll roll with the better team here giving a field goal at home.
Pick: Bengals -3
Pittsburgh Steelers vs. Indianapolis Colts Prediction
- Spread
Colts -2.5 - Moneyline
Steelers +110, Colts -130 - Total
42.5
My successful ride on the Colts Express ended last week, but we aren’t hopping off of it just yet.
Stinkers like the loss to the hot Bengals are going to happen, but Indy is right there in the AFC race and needs this one against a fellow playoff contender in Pittsburgh.
While I’m a believer in the Colts, I do not feel the same way about the Steelers, who have lost two straight games and have been out-gained in 11 of 13 contests this season. It’s a miracle this team is 7-6 and the current sixth seed in the AFC. I’m betting on the Colts yet again.
Pick: Colts -1.5 (best bet)
Denver Broncos vs. Detroit Lions Prediction
- Spread
Lions -4 - Moneyline
Broncos +170, Lions -200 - Total
47.5
This is a matchup of two teams heading in opposite directions, as the Lions have lost two of their last three games, and the Broncos have won six of their last seven. If only betting on the NFL was that easy.
It’s hard to understate the turnaround the Broncos have done this year, from an 0-3 start and allowing 70 points against the Dolphins to now being over .500 and right there in the playoff hunt (no, Sean Payton is not COY).
The Lions, despite recent struggles, will still win the NFC North and likely will fix things before the postseason, but they aren’t this many points better than the Broncos right now. Maybe in Week 10.
Pick: Broncos +4
Tampa Bay Buccaneers vs. Green Bay Packers Prediction
- Spread
Packers -3.5 - Moneyline
Buccaneers +150, Packers -175 - Total
41.5
The “Battle of the Bays.” Neither one of these teams have any staying power if they make the postseason, and neither is very consistent. It’s difficult to handicap this one because you never know which team will show up, so it’s a pass. I would lean toward the over here since both defenses have shown troubles during the last month, but it’s not a strong lean.
Pick: Lean over 41.5
New York Giants vs. New Orleans Saints Prediction
- Spread
Saints -6 - Moneyline
Giants +220, Saints -270 - Total
37.5
The Saints really shouldn’t be a six-point favorite over anyone. Yes, they won by three touchdowns last week, but that was against the one-win Panthers. I’m not yet buying the Giants’ playoff run, but the Tommy DeVito mania is real. With the way the Giants are playing, six points is too much not to take here.
Pick: Giants +6
Atlanta Falcons vs. Carolina Panthers Prediction
- Spread
Falcons -3 - Moneyline
Falcons -165, Panthers +140 - Total
35.5
Someone has to win the NFC South, right? Well, it won’t be the Panthers, and the Falcons blew their chance to basically put it away last week, allowing a touchdown to the Buccaneers with less than four minutes to go.
MORE: PFN’s FREE NFL Playoff Predictor
Bottom line, neither team should be trusted, as I am not laying three points with the Falcons, and I can’t advise people to bet on the Panthers, who are the worst team both straight up and against the spread this season (2-9-2 ATS).
Pick: Pass
Houston Texans vs. Tennessee Titans Prediction
- Spread
Titans -3 - Moneyline
Texans +120, Titans -140 - Total
37.5
This game will all depend on C.J. Stroud’s health and if he passes concussion protocol.
If he can’t go, I will stay far away from this one. Even with Stroud last week, the Texans’ offense was a mess without Tank Dell — 135 total yards speaks for itself.
The Titans shocked Miami on Monday night but will face a short turnaround and be in a natural letdown situation. No one would’ve had the Titans favored in this matchup a week ago, but so much changes week-to-week in the NFL.
The value is on the Texans getting points, but without Stroud, you don’t want any part of it. Should he play, this line would move closer to even.
Pick: Pass for now
New York Jets vs. Miami Dolphins Prediction
- Spread
Dolphins -8.5 - Moneyline
Jets +360, Dolphins -450 - Total
39.5
OK. I kind of talked myself into this while being a pinch hitter on the Miami Dolphins podcast this week.
I haven’t bet any sort of under in a Dolphins game (except the Jets team total under in the first matchup) this season, as Miami’s offense has been very explosive. However, things have changed, most notably the season-ending ACL injury to center Conor Williams and receiver Tyreek Hill having a banged-up ankle.
Without Williams and Hill for half of the game against the Titans, the Dolphins’ offense was a shell of itself against an average defense. What will it look like against a great Jets defense that intercepted Tua twice and held him in check the last time they played? Miami will have to find success on the ground like they did on Black Friday at the Meadowlands.
As for the Jets’ offense, congrats to Zach Wilson for 1.5 quarters of good football. Not sure that happens again.
Pick: Under 37.5 (and I don’t take this with a smile)
Chicago Bears vs. Cleveland Browns Prediction
- Spread
Browns -3 - Moneyline
Bears +150, Browns -175 - Total
37.5
The Cleveland Browns are a contender. The Browns won’t make the playoffs. The Browns are a contender. The Browns stink. That’s the world of the Browns, who have been as up and down as any team this season, sometimes within the same game as we saw in their survival vs. the Jags on Sunday.
The Bears started horrible but have been a sneaky spoiler team that finds itself on the edge of the NFC playoff race.
I don’t trust either team but lean toward taking the points with an improving Bears team, who can spoil their own draft place as they also have the Panthers’ first-round pick.
Pick: Pass
Kansas City Chiefs vs. New England Patriots Prediction
- Spread
Chiefs -7.5 - Moneyline
Chiefs -400, Patriots +320 - Total
37.5
Recency bias would say to take the points with the home team coming off their best game of the season on a long week of rest. Nah. This is a great get-right spot for the Chiefs, who all of a sudden find themselves in a battle with the Broncos to win the division. It’s not my favorite pick, but the Chiefs figure it out.
Pick: Chiefs -7.5
Washington Commanders vs. Los Angeles Rams Prediction
- Spread
Rams -6.5 - Moneyline
Commanders +240, Rams -290 - Total
49.5
The Commanders are as good as done for 2023, and it won’t be surprising to see the new owner clean house two minutes after the season ends. You couldn’t see any fight in Washington the last time we saw them play, getting blown out by the Dolphins at home.
MORE: NFL Survivor Picks Week 15
The Rams are very much alive in the NFC and should have beaten the Ravens in Baltimore last week. They are a team to keep an eye on down the stretch and should win this one easily.
Pick: Rams -6.5 (best bet)
San Francisco 49ers vs. Arizona Cardinals Prediction
- Spread
49ers -13.5 - Moneyline
49ers -900, Cardinals +600 - Total
47.5
The Niners are now 10-0 with nine double-digit wins when Trent Williams and Deebo Samuel are healthy and on the field. The one game that wasn’t a double-digit win was when Rams coach Sean McVay kicked a meaningless FG (to some).
As a rule, I don’t normally lay double digits in the NFL, especially on the road, and last week, I got the Niners at -10 before the line ran up to the same 13.5 that it is now. Seattle covered the 13.5 but not my 10, so I won it by getting it early.
If forced to play the game, I would lay it, but that’s the beauty — you don’t have to play it.
Pick: Pass, but lean SF -13.5
Dallas Cowboys vs. Buffalo Bills Prediction
- Spread
Bills -2 - Moneyline
Cowboys +105, Bills -125 - Total
50.5
The narrative is the Bills are back, going to sneak into the playoffs, and come from deep down to win the AFC. Slow down for a second. The win in Arrowhead last week was the first victory vs. a good team since Week 3 vs. Miami. The same can be said for the Cowboys, who beat an above .500 team in the Eagles last week for the first time all season.
However, the ‘Boys have been far more consistent this season than Buffalo and, to put it simply, are the better team. Since getting blowout by the Niners back in September, the Cowboys are 8-1, with the one excpetion being a five-point loss at Philly. They have the best offense in the league right now, scoring 33+ points in six of seven since the bye.
The Cowboys will be away from home and in rowdy Buffalo, but the Bills’ defense has been their soft spot all season. I think the Cowboys keep rolling here.
Pick: Cowboys +2
Baltimore Ravens vs. Jacksonville Jaguars Prediction
- Spread
Ravens -3 - Moneyline
Ravens -165, Jaguars +140 - Total
42.5
With Trevor Lawrence banged up and injuries all over the place, the Jags are no the same team that was on the cusp of controlling their own destiny in the AFC. Now, they host arguably the best team in the AFC: the Ravens.
Pick: Ravens -3
Philadelphia Eagles vs. Seattle Seahawks Prediction
- Spread
Eagles -4 - Moneyline
Eagles -195, Seahawks +165 - Total
47.5
The Eagles team you saw in Weeks 13-14 are not the same ones you saw in the first 12 weeks of the season. There were a few early games they should not have won, but they didn’t come close to playing as bad as they did in “big boy” games vs. the Niners and Cowboys. The defense looks tired and horrible, while the offense couldn’t generate anything last week.
A little nugget a former colleague at ESPN gave me: Underdogs are 6-0 straight up over the last five weeks in MNF games, including two big underdogs last week in the Giants and Titans. That’s tied for the longest streak of dogs winning outright on MNF since the first six weeks of the 1985 season. Fly, Seahawks, fly.
Pick: Seahawks +4
Our Betting Lines page has the freshest lines and promos to get BANG for your buck. PFN’s FREE Parlay Calculator and Betting Odds Calculator are also available for your betting process! New to sports betting? Check out our guide on How to Bet on the NFL. Visit our Sports Betting Legal Tracker on how to bet legally in the U.S.
