The Kansas City Chiefs vs. San Francisco 49ers preseason game brings us a repeat of the Super Bowl in 2020 before both teams kick off their 2021 campaigns. What is the start time, current NFL odds, TV channel, and how to live stream the Chiefs vs. 49ers NFL preseason Week 1 game?
Kansas City Chiefs vs. San Francisco 49ers | Preseason Week 1
How can you watch this week’s matchup between the Chiefs and 49ers, and what time is it on?
How to watch, live streams, TV channel, & more
- Start time: 8:30 PM ET, August 14
- Location: Levi’s Stadium, Santa Clara, CA
- TV channel: KSHB (Kansas City), KPIX 5 (San Francisco)
- Live stream options:
- YouTubeTV
- Hulu
- fuboTV
- AT&T TV
- PS Vue
- Paramount+ (KPIX)
- NFL Game Pass
Check with your streaming service to confirm the availability of specific channels.
Chiefs vs. 49ers | Current NFL odds, spreads, betting lines, and predictions
- Spread: 49ers -2.5 (-115)
- Moneyline: 49ers -150, Chiefs +130
- Total: 37 (Over -135, Under +115)
Intriguingly, the 49ers are the favorites for this matchup with the majority of sportsbooks. In many, they sit as 2.5-point favorites but are as low as 1-point favorites at Bet America.
The total for this game is among the highest of Week 1 of the 2021 NFL preseason. There is also a reasonably wide variation across the sportsbooks. The lowest total at the major sportsbooks is 36.5, with the highest being 38.
Chiefs vs. 49ers series history
The 49ers and Chiefs have faced off a total of 14 times. The 49ers own the head-to-head in the regular season 7-6. Yet, in the most important meeting between the two — Super Bowl LIV — the Chiefs took the victory. Therefore, the overall series stands at 7-7.
Here are the last five meetings between the two teams.
- Chiefs 41-0 49ers | 2006
- Chiefs 31-10 49ers | 2010
- 49ers 22-17 Chiefs | 2014
- Chiefs 38-27 49ers | 2018
- Chiefs 31-20 49ers | 2020
In Super Bowl LIV, the 49ers took a 20-10 lead heading into the fourth quarter. However, the Chiefs scored an unanswered 21 points — including 2 touchdowns from Damien Williams in the final three minutes — to win the game 31-20. That was the Chiefs’ fourth win in the last five meetings between the two teams.
Chiefs 2021 preseason schedule
- Week 1 | @ San Francisco 49ers | August 14
- Week 2 | @ Arizona Cardinals | August 20
- Week 3 | vs. Minnesota Vikings | August 27
49ers 2021 preseason schedule
- Week 1 | vs. Kansas City Chiefs | August 14
- Week 2 | at Los Angeles Chargers | August 22
- Week 3 | vs. Las Vegas Raiders | August 29
Ben Rolfe is a Senior Managing Editor at Pro Football Network and is also a member of the Fantasy Sports Writers Association (FSWA). You can find him on Twitter @BenRolfePFN.