The San Francisco 49ers will face the Los Angeles Rams in Week 15. Here’s the latest fantasy football news and advice to help you with your lineups this week and moving forward, especially regarding RB Isaac Guerendo.
Is Isaac Guerendo Playing in Week 15?
Already down Christian McCaffrey and Jordan Mason, the San Francisco 49ers had to turn to Guerendo in Week 14. The rookie performed extremely well, running the ball 15 times for 78 yards and two touchdowns while catching two passes for 50 yards.
Unfortunately, Guerendo sprained his foot late in the second half. He was listed as a non-participant in Monday’s estimated practice report and did not practice on Tuesday either. Despite the short week, though, Guerendo was able to get in a limited session on Wednesday, drawing a questionable tag.
If Guerendo can’t go, Patrick Taylor Jr. would get the start on Thursday night in a very favorable matchup against a soft Rams run defense.
We’ll continue to monitor the 49ers injury report. You can also visit and bookmark our NFL Injury Tracker and Fantasy News Tracker for the latest updates.
Should You Start or Sit Isaac Guerendo in Week 15?
On Sunday, Guerendo became the first player in the NFL this season with a rushing TD and 50 receiving yards in a first quarter — not bad for his first week at the controls of Kyle Shanahan’s backfield.
A foot injury suffered late last week has Guerendo sitting out of practice to open Week 15. Should their third string RB miss time, Patrick Taylor Jr. and Ke’Shawn Vaughn are the next men up. At some point, this running game is likely to struggle, but I need to see it before projecting it.
Guerendo is going to check in as a solid RB2 for me if he plays. Should he sit, Taylor won’t be far behind.
The Rams are the fifth-worst rushing defense by yards allowed per game and third-down conversion rate on the ground. The 49ers should have success when they hand the ball off, it’s just who to determine will get the bulk of those attempts.
Deebo Samuel Sr. is likely to eat into the RB workload, making it possible that he is a cheat code for DFS showdown contests.
Are you looking for start/sit advice for other players in your lineup? Read our Week 15 Fantasy Start-Sit Advice Cheat Sheet for every fantasy-relevant player in every game.
Isaac Guerendo’s Fantasy Points Projection in Week 15
As of Thursday evening, Guerendo is projected to score 13.3 fantasy points in PPR formats. This includes 15.5 rushing attempts for 69.9 yards and 0.4 touchdowns. It also includes 1.2 receptions for 24 yards and 0.1 touchdowns.
Check out the free PFN Fantasy Start-Sit Optimizer for the latest projections and advice for your lineups this week.
Isaac Guerendo’s Fantasy Ranking
Our Weekly Consensus PPR Rankings are below — both positional and overall. They were last updated at 11:45 PM ET on Saturday, January 25.
Conference Championship RB PPR Rankings
1) Saquon Barkley | PHI (vs. WAS)
2) James Cook | BUF (at KC)
3) Brian Robinson Jr. | WAS (at PHI)
4) Isiah Pacheco | KC (vs. BUF)
5) Kareem Hunt | KC (vs. BUF)
6) Austin Ekeler | WAS (at PHI)
7) Ray Davis | BUF (at KC)
8) Ty Johnson | BUF (at KC)
9) Samaje Perine | KC (vs. BUF)
10) Kenneth Gainwell | PHI (vs. WAS)
11) Jeremy McNichols | WAS (at PHI)
12) Will Shipley | PHI (vs. WAS)
13) Carson Steele | KC (vs. BUF)
14) Reggie Gilliam | BUF (at KC)
15) Chris Rodriguez Jr. | WAS (at PHI)
