The San Francisco 49ers will face the Detroit Lions in Week 17. Here’s the latest fantasy football news and advice to help you with your lineups this week and moving forward, especially regarding RB Isaac Guerendo.
Is Isaac Guerendo Playing in Week 17?
After missing last week’s game with a hamstring strain, Guerendo was back on the practice field Thursday, getting in a limited session. He was limited again on Friday. The rookie is expected to return to the RB1 role on Monday night.
We’ll continue to monitor the 49ers injury report. You can also visit and bookmark our NFL Injury Tracker and Fantasy News Tracker for the latest updates.
Isaac Guerendo’s Fantasy Outlook
A hamstring injury cost Isaac Guerendo last week and could well end his season, given that the team has nothing left to play for.
That said, we’ve seen teams make questionable health decisions like this in the past, and if we get sparkling health reports, you’d almost be obligated to Flex this role from a process standpoint.
San Francisco’s bell-cow role, percentage of RB touches:
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- Weeks 1-2, Jordan Mason: 87.5%
- Weeks 10-11, Christian McCaffrey: 89.3%
- Weeks 14-15, Guerendo (minus Q4 of Week 14): 94.4%
- Week 16, Patrick Taylor Jr.: 81.8%%
Patrick Taylor didn’t have much of a chance to impress last week, making it even more likely that the feature role would be Guerendo’s if he is fit enough for it.
Keep tabs. I’m benching Guerendo right now and pivoting should things flip.
Are you looking for start/sit advice for other players in your lineup? Read our Week 17 Fantasy Start-Sit Advice Cheat Sheet for every fantasy-relevant player in every game.
Isaac Guerendo’s Fantasy Points Projection in Week 17
As of Saturday, Guerendo is projected to score 12.9 fantasy points in PPR formats. This includes 15 rushing attempts for 67.5 yards and 0.4 touchdowns. It also includes 1.2 receptions for 23.1 yards and 0.1 touchdowns.
Check out the free PFN Fantasy Start-Sit Optimizer for the latest projections and advice for your lineups this week.
Isaac Guerendo’s Fantasy Ranking
Our Weekly Consensus PPR Rankings are below — both positional and overall. They were last updated at 12:45 AM ET on Friday, December 27. If you're in a Superflex league, make sure you check out our Weekly Consensus Superflex Rankings.
Week 17 RB PPR Rankings
1) Saquon Barkley | PHI (vs. DAL)
2) Jahmyr Gibbs | DET (at SF)
3) Derrick Henry | BAL (at HOU)
4) Bijan Robinson | ATL (at WAS)
5) Josh Jacobs | GB (at MIN)
6) De'Von Achane | MIA (at CLE)
7) Jonathan Taylor | IND (at NYG)
8) Chase Brown | CIN (vs. DEN)
9) Kyren Williams | LAR (vs. ARI)
10) James Conner | ARI (at LAR)
11) Bucky Irving | TB (vs. CAR)
12) Chuba Hubbard | CAR (at TB)
13) James Cook | BUF (vs. NYJ)
14) Breece Hall | NYJ (at BUF)
15) Joe Mixon | HOU (vs. BAL)
16) Zach Charbonnet | SEA (at CHI)
17) Aaron Jones | MIN (vs. GB)
18) Jerome Ford | CLE (vs. MIA)
19) Brian Robinson Jr. | WAS (vs. ATL)
20) Tony Pollard | TEN (at JAX)
21) Rico Dowdle | DAL (at PHI)
22) D'Andre Swift | CHI (vs. SEA)
23) Isaac Guerendo | SF (vs. DET)
24) Rhamondre Stevenson | NE (vs. LAC)
25) Rachaad White | TB (vs. CAR)
26) J.K. Dobbins | LAC (at NE)
27) Alexander Mattison | LV (at NO)
28) Isiah Pacheco | KC (at PIT)
29) Kendre Miller | NO (vs. LV)
30) Tyjae Spears | TEN (at JAX)
31) Travis Etienne Jr. | JAX (vs. TEN)
32) Jaylen Warren | PIT (vs. KC)
33) Javonte Williams | DEN (at CIN)
34) Tank Bigsby | JAX (vs. TEN)
35) Gus Edwards | LAC (at NE)
36) Kimani Vidal | LAC (at NE)
37) Najee Harris | PIT (vs. KC)
38) Ameer Abdullah | LV (at NO)
39) Kareem Hunt | KC (at PIT)
40) Devin Singletary | NYG (vs. IND)
41) Tyler Allgeier | ATL (at WAS)
42) Audric Estimé | DEN (at CIN)
43) Ray Davis | BUF (vs. NYJ)
44) Raheem Mostert | MIA (at CLE)
45) Antonio Gibson | NE (vs. LAC)
46) Kenneth Gainwell | PHI (vs. DAL)
47) Craig Reynolds | DET (at SF)
48) Cam Akers | MIN (vs. GB)
49) Ty Johnson | BUF (vs. NYJ)
50) Blake Corum | LAR (vs. ARI)
51) Patrick Taylor Jr. | SF (vs. DET)
52) Roschon Johnson | CHI (vs. SEA)
53) Braelon Allen | NYJ (at BUF)
54) Jeremy McNichols | WAS (vs. ATL)
55) Jaleel McLaughlin | DEN (at CIN)
56) Isaiah Davis | NYJ (at BUF)
57) D'Onta Foreman | CLE (vs. MIA)
58) Jamaal Williams | NO (vs. LV)
59) Cordarrelle Patterson | PIT (vs. KC)
60) Emanuel Wilson | GB (at MIN)
61) DeeJay Dallas | ARI (at LAR)
62) Chris Brooks | GB (at MIN)
63) Pierre Strong Jr. | CLE (vs. MIA)
64) Keaton Mitchell | BAL (at HOU)
65) Trey Benson | ARI (at LAR)
66) Ke'Shawn Vaughn | SF (vs. DET)
67) Sean Tucker | TB (vs. CAR)
68) Tyrone Tracy Jr. | NYG (vs. IND)
69) Israel Abanikanda | SF (vs. DET)
70) Samaje Perine | KC (at PIT)
71) Michael Carter | ARI (at LAR)
72) Ezekiel Elliott | DAL (at PHI)
73) Khalil Herbert | CIN (vs. DEN)
74) Dare Ogunbowale | HOU (vs. BAL)
75) Jaylen Wright | MIA (at CLE)
76) Kyle Juszczyk | SF (vs. DET)
77) Trey Sermon | IND (at NYG)
78) Mike Boone | CAR (at TB)
79) Chris Rodriguez Jr. | WAS (vs. ATL)
80) Sione Vaki | DET (at SF)
81) Dameon Pierce | HOU (vs. BAL)
82) Hunter Luepke | DAL (at PHI)
83) Alec Ingold | MIA (at CLE)
84) Tyler Goodson | IND (at NYG)
85) Will Shipley | PHI (vs. DAL)