The Arizona Cardinals, who were very competitive over their first three games, are suddenly looking like the struggling team many predicted before the season, losing three in a row by double digits. Will they be able to keep it close with the Seahawks in Seattle? Take a look at our breakdown of this matchup.
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Cardinals vs. Seahawks Betting Lines, Start Time, and More
All odds from DraftKings Sportsbook.
- Spread: Seahawks -7.5
- Moneyline: Cardinals (+310); Seahawks (-395)
- Over/Under: 44.5
- Game time: 4:05 p.m. ET
- Location: Lumen Field
- Channel: FOX
Cardinals vs. Seahawks Prediction
On the surface, there shouldn’t be any question that Seattle is the better team in its matchup with Arizona. Never mind the overall records — one team (Seattle) has both its starting quarterback and running back in the lineup in Geno Smith and Kenneth Walker III.
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Arizona, meanwhile, goes another week without Kyler Murray (knee) and James Conner (knee). Plus, the Cardinals are coming off a loss to the Rams last week in which they scored a season-low nine points, thanks to three measly field goals.
Without Conner in the lineup last week, quarterback Joshua Dobbs led the team in rushing vs. the Rams with 47 yards. As for his passing, after a strong start to the season — back-to-back games with a passer rating over 100 in Weeks 3 and 4 — Dobbs has had a passer rating under 60 in each of his last two games.
Arizona also has been making mistakes — five turnovers over the last two weeks — after going three straight weeks without one.
Seattle, which is tied for sixth in the NFL with 19 sacks, figures to get after Dobbs, who has been sacked five times over the last two games. The Seahawks have seven different players who have at least two sacks this season, the most in the NFL.
Offensively, the Seahawks led a golden opportunity to get a third straight road win to begin their season. But they failed to score in two red-zone drives at the end of the game and fell to the Bengals in Cincinnati. Overall, Seattle scored just one touchdown in six red-zone trips vs. the Bengals.
The Seahawks also had more turnovers last week (2) than they had in their first four games combined (1).
Despite throwing for 326 yards, Smith had his worst game of the season, finishing without a TD pass for the first time this season and throwing a season-high two interceptions. His passer rating of 69.8 was a season-low, and Smith was also sacked a season-high four times.
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But the Cardinals defense does not figure to pose much of a threat when the Seahawks are on offense. Arizona is on a streak of five consecutive games, allowing at least 380 total yards. That is tied for the longest active streak in the NFL, along with the Commanders and Broncos.
The good news for Arizona is safety Budda Baker is expected to return to the lineup. Baker had been on the IR with a hamstring issue but should be able to play Sunday.
The Cardinals have absolutely flopped in divisional games of late, going just 1-7 against the spread in games vs. NFC West opponents (0-2 ATS this season). Trying to change that trend in a place like Seattle isn’t exactly an ideal situation.
Taking the Seahawks, even at home, when the spread is more than a touchdown, is a little on the risky side. But so is getting behind a Cardinals team down their starting quarterback and running back.
I will gladly give the points here.
Best Bet: Seahawks -7.5 (-108 at DraftKings Sportsbook)