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    NFL Week 7 Odds and Betting Trends Against the Spread: Patrick Mahomes vs. Justin Herbert, Tua Tagovailoa vs. Jalen Hurts, and More

    The NFL Week 7 odds feature more than a few interesting marquee matchups -- what teams can you trust now that we have six weeks of data?

    The NFL Week 7 betting odds reflect some chaos at the quarterback position and a pair of marquee matchups among the elite at the position. Before you place a single bet for the week, make sure you check out the most recent trends for all 26 teams in action.

    How are we using these trends? The PFN Betting Podcast runs through every single game as we head into the weekend!

    Our Betting Lines page has the freshest lines and promos to get BANG for your buck. PFN’s FREE Parlay Calculator and Betting Odds Calculator are also available for your betting process! New to sports betting? Check out our guide on How to Bet on the NFL. Visit our Sports Betting Legal Tracker on how to bet legally in the U.S.

    NFL Week 7 Odds and Betting Trends

    All odds are from DraftKings Sportsbook and trends from Inside Edge.

    Jacksonville Jaguars vs. New Orleans Saints Odds

      • Spread
        Saints -3
      • Moneyline
        Jaguars +130. Saints -155
      • Total
        39

    Under tickets have cashed 62.1% of the time when Jacksonville is an underdog since the beginning of 2021.

    MORE: Sportsbooks Seem Unsure if Trevor Lawrence Will Play

    The Saints are 2-8-1 ATS since the beginning of last season when favored.

    Las Vegas Raiders vs. Chicago Bears Odds

      • Spread
        Raiders -3
      • Moneyline
        Raiders -155, Bears +130
      • Total
        37.5

    The Raiders are the third-worst against the spread (ATS) road team since the beginning of last season (4-8, the only teams worse over that stretch both play at home this week: Chicago and Denver).

    Overs are 6-2 in Chicago’s past eight games against a bottom-10 offense.

    Cleveland Browns vs. Indianapolis Colts Odds

      • Spread
        Browns -2
      • Moneyline
        Browns -130, Colts +110
      • Total
        39

    Unders are 9-1 following a Browns home win since the beginning of 2021.

    Unders are 10-3 in Indianapolis’ past 13 games against a bottom-10 pass offense.

    Buffalo Bills vs. New England Patriots Odds

      • Spread
        Bills -9
      • Moneyline
        Bills -410, Patriots +320
      • Total
        41.5

    The Bills have outscored the Patriots 95-40 in their past three trips to Foxborough in the post-Tom Brady era.

    No team is worse against the spread versus top 10 offenses since the beginning of last season than the Patriots (1-7).

    Washington Commanders vs. New York Giants Odds

      • Spread
        Commanders -2
      • Moneyline
        Commanders -125, Giants +105
      • Total
        39.5

    Three straight games in this rivalry have seen no more than 40 points scored, with five of the past six seeing 43 or fewer points scored.

    Unders are 10-1-2 since 2021 when the Giants are a home underdog.

    Atlanta Falcons vs. Tampa Bay Buccaneers Odds

      • Spread
        Buccaneers -2.5
      • Moneyline
        Falcons +114, Buccaneers -135
      • Total
        38.5

    The Falcons are 4-10 ATS in their past 14 games against a top-10 run defense.

    The Bucs are the worst home ATS team since the beginning of last season (2-8).

    Detroit Lions vs. Baltimore Ravens Odds

      • Spread
        Ravens -3
      • Moneyline
        Lions +140, Ravens -166
      • Total
        42

    Under Dan Campbell, the Lions are 20-9 ATS as an underdog (69% cover rate, fourth best).

    Since the beginning of last season, unders are 9-1 in Baltimore home games.

    Pittsburgh Steelers vs. Los Angeles Rams Odds

      • Spread
        Rams -3
      • Moneyline
        Steelers +136, Rams -162
      • Total
        43.5

    The Steelers have covered 16 of their past 25 games as an underdog (64%).

    The Rams and Dolphins are the only teams unbeaten ATS when favored this season (minimum of two games as a favorite).

    Arizona Cardinals vs. Seattle Seahawks Odds

      • Spread
        Seahawks -8
      • Moneyline
        Cardinals +300, Seahawks -380
      • Total
        44.5

    The road team has won three of the past four games in this rivalry, with all three of those wins coming by at least eight points.

    MORE: Early NFL Week 7 Predictions and Picks Against the Spread

    The Seahawks have failed to cover six of nine games when favored since the beginning of last season.

    Green Bay Packers vs. Denver Broncos Odds

      • Spread
        Packers -1
      • Moneyline
        Packers -115, Broncos -105
      • Total
        44.5

    The Packers have covered eight of their past 12 games against a bottom-10 offense.

    Green Bay had the bye week to prepare for the altitude in Denver, an advantage that is lessening with time. Denver is 3-8 ATS in their last 11 home games.

    Los Angeles Chargers vs. Kansas City Chiefs Odds

      • Spread
        Chiefs -5.5
      • Moneyline
        Chargers +200, Chiefs -245
      • Total
        49

    Overs are 10-2-1 following a Chargers loss since 2021, the highest hit rate in the NFL.

    The Chiefs are the fifth-worst ATS team since the beginning of last season in divisional games (2-5; only Seattle, New Orleans, Arizona, and Chicago have been worse).

    Miami Dolphins vs. Philadelphia Eagles Odds

      • Spread
        Eagles -2
      • Moneyline
        Dolphins +105, Eagles -125
      • Total
        52

    The Dolphins are 12-6 ATS following an outright win since the beginning of 2021.

    Overs are 14-5 in Philadelphia home games since the start of 2021, the highest hit rate in the NFL.

    San Francisco 49ers vs. Minnesota Vikings Odds

      • Spread
        49ers -6.5
      • Moneyline
        49ers -290, Vikings +235
      • Total
        43.5

    Overs are 10-5 in San Francisco’s past 15 games against bottom-10 pass defenses.

    Overs are 10-4 in Minnesota’s last 14 games against top-10 defenses.

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