Setting flex rankings for any given week is always tough — Week 5 of the 2021 fantasy football season is no exception. Knowing how to value the RBs, WRs, and TEs on your roster relative to each other based on their matchups each week can often leave you scratching your head. Therefore, to help give you some guidance, here are PFN’s Week 5 Flex Rankings.
The below rankings are intended as a guide for half-PPR formats. They do not take into account individual league rules and setups. The Week 5 flex rankings are from Fantasy Analyst Tommy Garrett.
Week 5 Fantasy Football Flex Rankings | 1-30
1. Derrick Henry | RB | Tennessee Titans @ JAX
2. Davante Adams | WR | Green Bay Packers @ CIN
3. Alvin Kamara | RB | New Orleans Saints @ WAS
4. Tyreek Hill | WR | Kansas City Chiefs vs. BUF
5. Aaron Jones | RB | Green Bay Packers @ CIN
6. Ezekiel Elliott | RB | Dallas Cowboys vs. NYG
7. Stefon Diggs | WR | Buffalo Bills @ KC
8. DJ Moore | WR | Carolina Panthers vs. PHI
9. Austin Ekeler | RB | Los Angeles Chargers vs. CLE
10. Saquon Barkley | RB | New York Giants @ DAL
11. Travis Kelce | TE | Kansas City Chiefs vs. BUF
12. Justin Jefferson | WR | Minnesota Vikings vs. DET
13. Nick Chubb | RB | Cleveland Browns @ LAC
14. Najee Harris | RB | Pittsburgh Steelers vs. DEN
15. Dalvin Cook | RB | Minnesota Vikings vs. DET
16. A.J. Brown | WR | Tennessee Titans @ JAX
17. Jonathan Taylor | RB | Indianapolis Colts @ BAL
18. Darren Waller | TE | Las Vegas Raiders vs. CHI
19. Deebo Samuel | WR | San Francisco 49ers @ ARI
20. D’Andre Swift | RB | Detroit Lions @ MIN
21. Terry McLaurin | WR | Washington Football Team vs. NO
22. James Robinson | RB | Jacksonville Jaguars vs. TEN
23. Keenan Allen | WR | Los Angeles Chargers vs. CLE
24. Amari Cooper | WR | Dallas Cowboys vs. NYG
25. DeAndre Hopkins | WR | Arizona Cardinals vs. SF
26. CeeDee Lamb | WR | Dallas Cowboys vs. NYG
27. Leonard Fournette | RB | Tampa Bay Buccaneers vs. MIA
28. Chris Godwin | WR | Tampa Bay Buccaneers vs. MIA
29. Cordarrelle Patterson | WR | Atlanta Falcons vs. NYJ
30. Kareem Hunt | RB | Cleveland Browns @ LAC
RB/WR/TE options for Week 5 | 31-60
31. Ja’Marr Chase | WR | Cincinnati Bengals vs. GB
32. Adam Thielen | WR | Minnesota Vikings vs. DET
33. Mike Williams | WR | Los Angeles Chargers vs. CLE
34. Corey Davis | WR | New York Jets @ ATL
35. Marquise Brown | WR | Baltimore Ravens vs. IND
36. Mike Evans | WR | Tampa Bay Buccaneers vs. MIA
37. Chase Edmonds | RB | Arizona Cardinals vs. SF
38. Damien Williams | RB | Chicago Bears @ LV
39. Tee Higgins | WR | Cincinnati Bengals vs. GB
40. Diontae Johnson | WR | Pittsburgh Steelers vs. DEN
41. Clyde Edwards-Helaire | RB | Kansas City Chiefs vs. BUF
42. Antonio Brown | WR | Tampa Bay Buccaneers vs. MIA
43. Antonio Gibson | RB | Washington Football Team vs. NO
44. Tyler Boyd | WR | Cincinnati Bengals vs. GB
45. Emmanuel Sanders | WR | Buffalo Bills @ KC
46. Damien Harris | RB | New England Patriots @ HOU
47. T.J. Hockenson | TE | Detroit Lions @ MIN
48. Marvin Jones Jr. | WR | Jacksonville Jaguars vs. TEN
49. Zack Moss | RB | Buffalo Bills @ KC
50. Laviska Shenault Jr. | WR | Jacksonville Jaguars vs. TEN
51. Mark Andrews | TE | Baltimore Ravens vs. IND
52. Josh Jacobs | RB | Las Vegas Raiders vs. CHI
53. DeVonta Smith | WR | Philadelphia Eagles @ CAR
54. Kenny Golladay | WR | New York Giants @ DAL
55. Brandin Cooks | WR | Houston Texans vs. NE
56. Jaylen Waddle | WR | Miami Dolphins @ TB
57. Allen Robinson II | WR | Chicago Bears @ LV
58. Chuba Hubbard | RB | Carolina Panthers vs. PHI
59. Kyle Pitts | TE | Atlanta Falcons vs. NYJ
60. DeVante Parker | WR | Miami Dolphins @ TB
Week 5 Flex Rankings | 61-90
61. Mike Davis | RB | Atlanta Falcons vs. NYJ
62. Cole Beasley | WR | Buffalo Bills @ KC
63. Tim Patrick | WR | Denver Broncos @ PIT
64. Chase Claypool | WR | Pittsburgh Steelers vs. DEN
65. Odell Beckham Jr. | WR | Cleveland Browns @ LAC
66. Jamaal Williams | RB | Detroit Lions @ MIN
67. Latavius Murray | RB | New Orleans Saints vs. IND
68. Henry Ruggs III | WR | Las Vegas Raiders vs. CHI
69. Melvin Gordon III | RB | Denver Broncos @ PIT
70. Javonte Williams | RB | Denver Broncos @ PIT
71. Mike Gesicki | TE | Miami Dolphins @ TB
72. Jakobi Meyers | WR | New England Patriots @ HOU
73. Dawson Knox | TE | Buffalo Bills @ KC
74. Michael Pittman Jr. | WR | Indianapolis Colts @ BAL
75. Jamison Crowder | WR | New York Jets @ ATL
76. Hunter Renfrow | WR | Las Vegas Raiders vs. CHI
77. Darnell Mooney | WR | Chicago Bears @ LV
78. Michael Carter | RB | New York Jets @ ATL
79. Noah Fant | TE | Denver Broncos @ PIT
80. Elijah Mitchell | RB | San Francisco 49ers @ ARI
81. Dalton Schultz | TE | Dallas Cowboys vs. NYG
82. Robby Anderson | WR | Carolina Panthers vs. PHI
83. A.J. Green | WR | Arizona Cardinals vs. SF
84. Randall Cobb | WR | Green Bay Packers @ CIN
85. Tony Pollard | RB | Dallas Cowboys vs. NYG
86. Miles Sanders | RB | Philadelphia Eagles @ CAR
87. Dallas Goedert | TE | Philadelphia Eagles @ CAR
88. Nyheim Hines | RB | Indianapolis Colts @ BAL
89. Samaje Perine | RB | Cincinnati Bengals vs. GB
90. Christian Kirk | WR | Arizona Cardinals vs. SF
RB/WR/TE options for Week 5 | 91-120
91. Trey Sermon | RB | San Francisco 49ers @ ARI
92. JuJu Smith-Schuster | WR | Pittsburgh Steelers vs. DEN
93. Courtland Sutton | WR | Denver Broncos @ PIT
94. Sammy Watkins | WR | Baltimore Ravens vs. IND
95. Nelson Agholor | WR | New England Patriots @ HOU
96. Alexander Mattison | RB | Minnesota Vikings vs. DET
97. Robert Tonyan | TE | Green Bay Packers @ CIN
98. Kadarius Toney | WR | New York Giants @ DAL
99. Zach Pascal | WR | Indianapolis Colts @ BAL
100. Brandon Aiyuk | WR | San Francisco 49ers @ ARI
101. Olamide Zaccheaus | WR | Atlanta Falcons vs. NYJ
102. Kalif Raymond | WR | Detroit Lions @ MIN
103. Hunter Henry | TE | New England Patriots @ HOU
104. Devin Singletary | RB | Buffalo Bills @ KC
105. George Kittle | TE | San Francisco 49ers @ ARI
106. K.J. Osborn | WR | Minnesota Vikings vs. DET
107. J.D. McKissic | RB | Washington Football Team vs. NO
108. Deonte Harris | WR | New Orleans Saints @ WAS
109. James Conner | RB | Arizona Cardinals vs. SF
110. Kenneth Gainwell | RB | Philadelphia Eagles @ CAR
111. Myles Gaskin | RB | Miami Dolphins @ TB
112. Marquez Callaway | WR | New Orleans Saints @ WAS
113. Jared Cook | TE | Los Angeles Chargers vs. CLE
114. Ronald Jones II | RB | Tampa Bay Buccaneers vs. MIA
115. Rondale Moore | WR | Arizona Cardinals vs. SF
116. Curtis Samuel | WR | Washington Football Team vs. NO
117. Tyler Conklin | TE | Minnesota Vikings vs. DET
118. AJ Dillon | RB | Green Bay Packers @ CIN
119. Quintez Cephus | WR | Detroit Lions @ MIN
120. Mecole Hardman | WR | Kansas City Chiefs vs. BUF
Week 5 Flex Rankings | 121-150
121. Bryan Edwards | WR | Las Vegas Raiders vs. CHI
122. Kendrick Bourne | WR | New England Patriots @ HOU
123. Jonnu Smith | TE | New England Patriots @ HOU
124. Evan Engram | TE | New York Giants @ DAL
125. Kenyan Drake | RB | Las Vegas Raiders vs. CHI
126. Joe Mixon | RB | Cincinnati Bengals vs. GB
127. Terrace Marshall Jr. | WR | Carolina Panthers vs. PHI
128. Zach Ertz | TE | Philadelphia Eagles @ CAR
129. Maxx Williams | TE | Arizona Cardinals vs. SF
130. Jalen Reagor | WR | Philadelphia Eagles @ CAR
131. Elijah Moore | WR | New York Jets @ ATL
132. David Johnson | RB | Houston Texans vs. NE
133. Cameron Brate | TE | Tampa Bay Buccaneers vs. MIA
134. Mo Alie-Cox | TE | Indianapolis Colts @ BAL
135. Quez Watkins | WR | Philadelphia Eagles @ CAR
136. Austin Hooper | TE | Cleveland Browns @ LAC
137. Rashard Higgins | WR | Cleveland Browns @ LAC
138. Amon-Ra St. Brown | WR | Detroit Lions @ MIN
139. Dan Arnold | TE | Carolina Panthers vs. TEN
140. Josh Reynolds | WR | Tennessee Titans @ JAX
141. C.J. Uzomah | TE | Cincinnati Bengals vs. GB
142. Mark Ingram II | RB | Houston Texans vs. NE
143. Cole Kmet | TE | Chicago Bears @ LV
144. Allen Lazard | WR | Green Bay Packers @ CIN
145. Gabriel Davis | WR | Buffalo Bills @ KC
146. Devin Duvernay | WR | Baltimore Ravens vs. IND
147. Keelan Cole Sr. | WR | New York Jets @ ATL
148. Chris Conley | WR | Houston Texans vs. NE
149. Blake Jarwin | TE | Dallas Cowboys vs. NYG
150. Malcolm Brown | RB | Miami Dolphins @ TB